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Pozelimab

Product Item Number: XC978995-100µg English Name: Pozelimab Chinese Name: Pazelimumab

Commodity name： Pozelimab

Category:

Control drug

Email:

taoweihong@constreambio.com

Product Inquiry

Product Specifications

Product item number	XC978995-100µg
English name	Pozelimab
Chinese name	Pazolizumab
Antibody source	Human
Clone Type	Monoclonal
Physical State	Liquid
Concentration	1 mg/mL
Subtype	IgG4κ
Expression system	CHO-K1 stable cell line
Purification method	Affinity purified by Protein A
Buffer solution	0.2 μm filtered in PBS, pH 7.4, 10% glycerol
Purity	＞98% as determined by SDS-PAGE；＞98% as determined by SEC-HPLC

Storage conditions

Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

Precautions

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Introduction

Pozelimab is a human IgG4κ mAb that targets complement factor 5 (C5) to help prevent diseases mediated by the complement pathway，Pozelimab targets complement factor C5, a protein involved in the complement cascade, which plays a key role in inflammation and immune responses.By inhibiting C5, Pozelimab prevents the formation of C5a (a pro-inflammatory molecule) and C5b-9 (the membrane attack complex), which can cause tissue damage in certain diseases.

Documentary materials