SDS-PAGE
Anti-SN38 mAb on SDS-PAGE under reduced condition. The purity is 95.5%；
Anti-SN38 mAb on SDS-PAGE under non-reduced condition. The purity is 99.2%.
Anti-SN38 monoclonal antibody (Anti-SN38 mAb)
Product Number: XC992997 - 100 µg
English Name: Anti-SN38 mAb
Chinese Name: Anti-SN38 Monoclonal Antibody
- Commodity name： Anti-SN38 monoclonal antibody (Anti-SN38 mAb)
Detailed description
- Product Description
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Product Specifications
Product Number XC992997 -100µg English name Anti-SN38 mAb Chinese name Anti-SN38 monoclonal antibody Antibody source Mouse Clone Type Monoclonal Physical State Liquid Concentration 1 mg/mL Subtype IgG Expression system Hybridoma Purification method affinity purified by Protein G Buffer solution 0.2 μm filtered in PBS, pH 7.4 Purity ＞95% as determined by SDS-PAGE；＞98% as determined by SEC-HPLC Activity EC50=0.08048 μg/mL by ELISA Application ELISA, Sandwich ELISA, Competitive ELISA Storage conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Precautions
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage. Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38.
Image data
SEC-HPLC
The purity of Anti-SN38 mAb is 100.0% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-SN38 mAb is 0.08048 μg/mL.
Documentary materials
Keywords:
Reference drug | Anti-drug antibodies | Instrument | Reagent
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