Anti-MMAF monoclonal antibody

Product Number: XC993997-100μg English Name: Anti-MMAF mAb Chinese Name: Anti-MMAF Monoclonal Antibody
  • Commodity name: Anti-MMAF monoclonal antibody

Detailed description

  • Product Description
  • Product Specifications

    Product Number XC993997-100μg
    English name Anti-MMAF mAb
    Chinese name Anti-MMAF monoclonal antibody
    Antibody source Mouse
    Clone Type Monoclonal
    Physical State Liquid
    Concentration 1mg/mL
    Subtype IgG
    Expression system Hybridoma
    Purification method affinity purified by Protein G
    Buffer solution 0.2 μm filtered in PBS, pH 7.4
    Purity >95% as determined by SDS-PAGE;>90% as determined by SEC-HPLC
    Activity EC50=0.00330 μg/mL by ELISA
    Application ELISA, Sandwich ELISA, Competitive ELISA

    Storage conditions

    Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

    Precautions

    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Product Introduction

    Monomethyl auristatin F (MMAF) is a synthetic peptide analog of the natural compound dolastatin 10. MMAF is a microtubule inhibitor, disrupts the formation of microtubules. MMAF is often used in conjunction with monoclonal antibodies as part of an antibody-drug conjugate (ADC) therapy. Monoclonal anti-MMAF antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAF.

    Image data

    SDS-PAGE   
    anti-MMAF antibody, on SDS-PAGE under reduced condition.The purity is 92.3%;
    anti-MMAF antibody, on SDS-PAGE under non-reduced contition. The purity is 98.5%.

    SEC-HPLC   
    The purity of anti-MMAF antibody, is 91.2% as determined by SEC-HPLC.

    ELISA Data    
    Dose response curve shows that the EC50 of anti-MMAF antibody is 0.00330 μg/mL.

Documentary materials

Image Name

Anti-MMAF Monoclonal Antibody COA

Keywords:

Reference drug | Anti-drug antibodies | Instrument | Reagent

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