SDS-PAGE
Anti-DXD mAb on SDS-PAGE under reduced condition. The purity is 98%；
Anti-DXD mAb on SDS-PAGE under non-reduced condition. The purity is 98%.
Anti-DXD monoclonal antibody
Product Number: XC995997 - 100 µg
English Name: Anti-DXD mAb
Chinese Name: Anti-DXD Monoclonal Antibody
- Commodity name： Anti-DXD monoclonal antibody
Detailed description
- Product Description
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Product Specifications
Product Number XC995997 -100µg English name Anti-DXD mAb Chinese name Anti-DXD monoclonal antibody Antibody source Mouse Clone Type Monoclonal Physical State Liquid Concentration 1mg/mL Subtype IgG Expression system Hybridoma Purification method affinity purified by Protein G Buffer solution 0.2 μm filtered in PBS, pH 7.4, 10% glycerol Purity ＞98% as determined by SDS-PAGE；＞98% as determined by SEC-HPLC Activity EC50=0.03694 μg/mL by ELISA Application ELISA, Sandwich ELISA, Competitive ELISA Storage conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Precautions
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
Exatecan (DXD) is a synthetic derivative of the naturally occurring compound camptothecin. It binds to the topoisomerase 1-DNA complex, preventing DNA re-ligation, which results in the accumulation of DNA strand breaks and ultimately leads to cell death. A monoclonal anti-DXD antibody is produced from a hybridoma obtained from a mouse immunized with DXD.
Image data
SEC-HPLC
The purity of Anti-DXD mAb is 99.0% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-DXD mAb is 0.03694 μg/mL.
Documentary materials
Keywords:
Reference drug | Anti-drug antibodies | Instrument | Reagent
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