Home page

Recombinant mouse IL6 protein

Product Number: XC985997-500μg English Name: Recombinant Mouse IL6/Interleukin-6 Protein Chinese Name: Recombinant Mouse IL6 Protein

Commodity name： Recombinant mouse IL6 protein

Category:

Recombinant protein

Email:

taoweihong@constreambio.com

Product Inquiry

Product Specifications

Product Number	XC985997-500μg
English name	Recombinant Mouse IL6/Interleukin-6 Protein
Chinese name	Recombinant mouse IL6 protein
Alternative name	IL-6
Gene ID	16193
Research field	Neuroinflammation
Protein source	Mouse
Host expression	E. coli
Protein tag	N-terminal 6xHis-tag
Protein purity	>95% purity by SDS-PAGE under reduced conditions.
Expression region	Mouse IL6 Protein is expressed from E. coli cells. It contains AA （Phe 25 - Thr 211） (Accession # P08505), This protein was fused with the His tag at the N-terminus.
Predicted molecular weight	The protein has a calculated MW of 26 kDa
Physical State	Liquid
Buffer solution	0.2 μm filtered in PBS, pH 7.4, 50% glycerol

Storage conditions

Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

Precautions

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Introduction

Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.