Rozanolixizumab
- Commodity name： Rozanolixizumab
Details Description
- Product Description
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Product Parameters
Product Number XC978997 -100µg English Name Rozanolixizumab Chinese Name 罗扎诺利珠单抗 Antibody Source Human Clone Type Monoclonal Appearance Liquid Concentration 1mg/mL Subtype IgG4κ Expression System CHO-K1 stable cell line Purification Method Affinity purified by Protein A Buffer 0.2 μm filtered in PBS, pH 7.4, 10% glycerol Purity >98% as determined by SDS-PAGE；>98% as determined by SEC-HPLC Storage Conditions
Aliquot and store at -20°C to -80°C, Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
Rozanolixizumab is a humanized IgG4κ monoclonal antibody. On June 27, 2023, rozanolixizumab-noli was approved by the FDA for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AchR) or anti-muscle-specific tyrosine kinase (MuSK) antibody positive. Rozanolixizumab inhibits the neonatal Fc receptor (FcRn), which plays a key role in recycling immunoglobulin G (IgG) antibodies in the body. By blocking FcRn, Rozanolixizumab reduces the levels of pathogenic IgG antibodies, which are involved in autoimmune diseases.
Documents
Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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