Recombinant human IFN gamma protein (his-tag)

Product Number: XC989997-500µg English Name: Recombinant Human IFN gamma Protein Chinese Name: 重组人 IFN gamma 蛋白
  • Commodity name: Recombinant human IFN gamma protein (his-tag)

Details Description

  • Product Description
  • Product Parameters

    Product NumberXC989997-500µg
    English NameRecombinant Human IFN gamma Protein
    Chinese NameRecombinant Human IFN gamma Protein
    Other NamesIFG,IFI,IFNG,IFN gamma,Interferon Gamma
    Gene ID3458
    Research AreaNeuroinflammation
    Protein SourceHuman
    Expression HostE. coli
    Protein TagN-terminal 6xHis-tag
    Endotoxin<1 EU/mg as determined by TAL test
    Protein Purity>95% purity by SDS-PAGE under reduced conditions.
    Expression RegionHuman IFN-gamma Protein is expressed from E. coli cells. It contains AA (Gln 24 - Gln 166) (Accession # P01579), This protein was fused with the His tag at the N-terminus.
    Predicted Molecular WeightThe protein has a calculated MW of 18 kDa
    StateLiquid
    Buffer0.2 μm filtered in PBS, pH 7.4, 50% glycerol

    Storage Conditions

    Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

    Notes

    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Product Introduction

    IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.

    Image Data

    SDS-PAGE Electrophoresis 
    Lane M: Protein marker Lane 1: Reduced sample

Documents

Image Name

Recombinant Human IFN gamma Protein (his-tag) COA

Keywords:

Reference Drug | Antibody Drug | Instrument | Reagent

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