Recombinant human IFN gamma protein (his-tag)
- Commodity name: Recombinant human IFN gamma protein (his-tag)
Details Description
- Product Description
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Product Parameters
Product Number XC989997-500µg English Name Recombinant Human IFN gamma Protein Chinese Name Recombinant Human IFN gamma Protein Other Names IFG,IFI,IFNG,IFN gamma,Interferon Gamma Gene ID 3458 Research Area Neuroinflammation Protein Source Human Expression Host E. coli Protein Tag N-terminal 6xHis-tag Endotoxin <1 EU/mg as determined by TAL test Protein Purity >95% purity by SDS-PAGE under reduced conditions. Expression Region Human IFN-gamma Protein is expressed from E. coli cells. It contains AA (Gln 24 - Gln 166) (Accession # P01579), This protein was fused with the His tag at the N-terminus. Predicted Molecular Weight The protein has a calculated MW of 18 kDa State Liquid Buffer 0.2 μm filtered in PBS, pH 7.4, 50% glycerol Storage Conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
Image Data
SDS-PAGE Electrophoresis
Lane M: Protein marker Lane 1: Reduced sample
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Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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