SDS-PAGE
Anti-MMAE mAb on SDS-PAGE under reduced condition. The purity is 94.7%；
Anti-MMAE mAb on SDS-PAGE under non-reduced condition. The purity is 97.6%.
Anti-MMAE monoclonal antibody
Product Number: XC994997-100µg
English Name: Anti-MMAE mAb
Chinese Name: 抗MMAE单克隆抗体
- Commodity name： Anti-MMAE monoclonal antibody
Details Description
- Product Description
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Product Parameters
Product Number XC994997-100µg English Name Anti-MMAE mAb Chinese Name Anti-MMAE monoclonal antibody Antibody Source Mouse Clone Type Monoclonal State Liquid
Concentration 1mg/mL Subtype IgG Expression System Hybridoma Purification Method affinity purified by Protein G Buffer 0.2 μm filtered in PBS, pH 7.4 Purity ≥95% as determined by SDS-PAGE；≥98% as determined by SEC-HPLC Activity EC50=0.01415 μg/mL by ELISA Application ELISA, Sandwich ELISA, Competitive ELISA Storage Conditions
Aliquot and store at -20°C to -80°C, Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin. Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE.
Image Data
SEC-HPLC
The purity of Anti-MMAE mAb is 98.0% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-MMAE mAb is 0.01415 μg/mL.
Documents
Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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