SDS-PAGE
Anti-DM1 mAb on SDS-PAGE under reduced condition. The purity is 93.4%；
Anti-DM1 mAb on SDS-PAGE under non-reduced condition. The purity is 98.0%.
Anti-DM1 monoclonal antibody
Product Number: XC996997-100µg
English Name: Anti-DM1 mAb
Chinese Name: 抗DM1单克隆抗体
- Commodity name： Anti-DM1 monoclonal antibody
Details Description
- Product Description
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Product Parameters
Product Number XC996997-100µg English Name Anti-DM1 mAb Chinese Name Anti-DM1 Monoclonal Antibody Antibody Source Mouse Clone Type Monoclonal State Liquid Concentration IgG Subtype Hybridoma Expression System affinity purified by Protein G Purification Method 0.2 μm filtered in PBS, pH 7.4 Buffer 1mg/mL Purity ＞95% as determined by SDS-PAGE；＞95% as determined by SEC-HPLC Activity EC50=0.01917 μg/mL by ELISA Application ELISA, Sandwich ELISA, Competitive ELISA Storage Conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
DM1, also known as maytansine, is a microtubulin inhibitor, potentially conjugated with monoclonal antibodies to form antibody-drug conjugates(ADCs). DM1 as the toxin component of ADCs, exhibits strong anti-tumor activity by inhibiting cell division and inducing apoptosis. Monoclonal anti-DM1 antibody, is produced from a hybridoma which was obtained from a mouse immunized with DM-1.
Image Data
SEC-HPLC
The purity of Anti-DM1 mAb is 96.8% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-DM1 mAb is 0.01917μg/mL.
Documents
Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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