Recombinant human TNF-alpha protein
- Commodity name： Recombinant human TNF-alpha protein
Details Description
- Product Description
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Product Parameters
Product Number XC990996-500μg English Name Recombinant Human TNF-alpha Protein Chinese Name Recombinant Human TNF-alpha Protein Alias DIF; TNF-alpha; TNFA; TNFSF2 Gene ID 7124 Research Field Cancer Drug Targets Protein Source Human Expression Host E. coli Protein Tag no tag Endotoxin <1 EU/mg as determined by TAL test Protein Purity >95% purity by SDS-PAGE under reduced conditions. Expression Region Human TNF-alpha Protein is expressed from E. coli cells. It contains AA (Val 77 - Leu 233) (Accession # P01375) Predicted Molecular Weight The protein has a calculated MW of 17.5 kDa State Liquid Buffer 0.2 μm filtered in PBS, pH 7.4, 50% glycerol. Storage Conditions
Aliquot and store at -20°C to -80°C, Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only.
Product Introduction
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
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Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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