Recombinant human IL-15 protein (his-tag)
- Commodity name： Recombinant human IL-15 protein (his-tag)
Details Description
- Product Description
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Product Parameters
Product Number XC982997-500μg English Name Recombinant Human IL-15 Protein Chinese Name 重组人IL-15 蛋白 Alias IL15, Interleukin 15 Gene ID 3600 Research Field Immunology Protein Source Human Expression Host E. coli Protein Tag N-terminal 6xHis-tag Protein Purity >95% purity by SDS-PAGE under reduced conditions. Expression Region Human IL-15 Protein is expressed from E. coli cells. It contains AA （Asn 49 - Ser 162） (Accession # P40933), This protein was fused with the His tag at the N-terminus. Predicted Molecular Weight The protein has a calculated MW of 14.5 kDa State Liquid Buffer 0.2 μm filtered in PBS, pH 7.4, 50% glycerol Storage Conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.
Image Data
SDS-PAGE Electrophoresis
Lane M: Protein marker Lane 1: Reduced sample
Documents
Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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