Recombinant human IL6 protein (his-tag)
- Commodity name： Recombinant human IL6 protein (his-tag)
Details Description
- Product Description
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Product Parameters
Product Number XC983997-500μg English Name Recombinant Human IL-6 Protein Chinese Name Recombinant Human IL6 Protein Alias BSF2; HGF; HSF; IFNB2; IL6; Interleukin-6 Gene ID 3569 Research Area Neuroinflammation Protein Source Human Expression Host E. coli Protein Tag N-terminal 6xHis-tag Endotoxin <1 EU/mg as determined by TAL test Protein Purity >95% purity by SDS-PAGE under reduced conditions Expression Region Human IL-6 Protein is expressed from E. coli cells. It contains AA (Val 30 - Met 212) (Accession # P05231). This protein was fused with the His tag at the N-terminus Predicted Molecular Weight The protein has a calculated MW of 25kDa Buffer 0.2 μm filtered in PBS, pH 7.4, 50% glycerol Storage Conditions
Aliquot and store at -20°C to -80°C, Avoid repeat freeze-thaw cycles.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing
the transition from innate to acquired immunity.Image Data
SDS-PAGE Electrophoresis
Lane M: Protein marker Lane 1: Reduced sample
Documents
Keywords:
Reference Drug | Antibody Drug | Instrument | Reagent
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