Recombinant human IL-1 beta protein (his tag)

Product Number: XC984997-500μg English Name: Recombinant Human IL-1 beta Protein Chinese Name: 重组人IL-1 beta 蛋白
  • Commodity name: Recombinant human IL-1 beta protein (his tag)

Details Description

  • Product Description
  • Product Parameters

    Product Number XC984997-500μg
    English Name Recombinant Human IL-1 beta Protein
    Chinese Name Recombinant Human IL-1 beta Protein
    Alias IL-1; IL-1 beta; IL-1B; IL1-BETA; IL1F2
    Gene ID 3553
    Research Area Neuroinflammation
    Protein Source Human
    Expression Host E. coli
    Protein Tag N-terminal 6xHis-tag
    Endotoxin <1 EU/mg as determined by TAL test
    Protein Purity >95% purity by SDS-PAGE under reduced conditions.
    Expression Region Human IL-1 beta Protein is expressed from E. coli cells. It contains AA (Ala 117 - Ser 269) (Accession # P01584), This protein was fused with the His tag at the N-terminus
    Predicted Molecular Weight The protein has a calculated MW of 19.5kDa
    State Liquid
    Buffer 0.2 μm filtered in PBS, pH 7.4, 50% glycerol

    Storage Conditions

    Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

    Notes

    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Product Introduction

    Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).

    Image Data

    SDS-PAGE Electrophoresis
    Lane M: Protein marker Lane 1: Reduced sample

Documents

Image Name

Recombinant human IL-1 beta protein (his tag) COA

Keywords:

Reference Drug | Antibody Drug | Instrument | Reagent

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