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Mirikizumab

Product Item Number: XC978996-100µg English Name: Mirikizumab Chinese Name: 米吉珠单抗

Commodity name： Mirikizumab

Category:

Control drug

Email:

taoweihong@constreambio.com

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Product Specifications

Product item number	XC978996-100µg
English name	Mirikizumab
Chinese name	Migalastat
Antibody source	Human
Clone Type	Monoclonal
Physical State	Liquid
Concentration	1 mg/mL
Subtype	IgG4κ
Expression system	CHO-K1 stable cell line
Purification method	Affinity purified by Protein A
Buffer solution	0.2 μm filtered in PBS, pH 7.4, 10% glycerol
Purity	＞98% as determined by SDS-PAGE；＞98% as determined by SEC-HPLC

Storage conditions

Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

Precautions

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Introduction

Mirikizumab is a humanized anti-IL -23p19 IgG4 monoclonal antibody developed as a treatment for ulcerative colitis (UC) and Crohn’s disease. It targets interleukin-23 (IL-23) and binds to the p19 subunit of IL-23, a cytokine that plays a key role in promoting inflammation in autoimmune diseases. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab helps reduce the inflammatory response, which is central to conditions like ulcerative colitis and Crohn's disease.

Documentary materials