Mirikizumab
- Commodity name： Mirikizumab
Detailed description
- Product Description
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Product Specifications
Product item number XC978996-100µg English name Mirikizumab Chinese name Migalastat Antibody source Human Clone Type Monoclonal Physical State Liquid Concentration 1 mg/mL Subtype IgG4κ Expression system CHO-K1 stable cell line Purification method Affinity purified by Protein A Buffer solution 0.2 μm filtered in PBS, pH 7.4, 10% glycerol Purity ＞98% as determined by SDS-PAGE；＞98% as determined by SEC-HPLC Storage conditions
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
Precautions
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Introduction
Mirikizumab is a humanized anti-IL -23p19 IgG4 monoclonal antibody developed as a treatment for ulcerative colitis (UC) and Crohn’s disease. It targets interleukin-23 (IL-23) and binds to the p19 subunit of IL-23, a cytokine that plays a key role in promoting inflammation in autoimmune diseases. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab helps reduce the inflammatory response, which is central to conditions like ulcerative colitis and Crohn's disease.
Documentary materials
Keywords:
Reference drug | Anti-drug antibodies | Instrument | Reagent
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